Vitamin K1 injection induced localized scleroderma like lesion in pregnancy: A case report
Keywords:
Adverse Drug Reaction, Phytomenadione, Naranjo scale, Modified-Hartwig’s-criteriaAbstract
Cutaneous reaction due to Vitamin K1 (Phytomenadione) injection can present as hypersensitivity reaction at the injection site with morphea like lesion that can be deep seated, involving the dermis & subcutaneous tissue, several days or weeks after injection of vitamin K1. Texier Disease,which is a scleroderma like lesion secondary to vitamin K1 injection is one of the rarely encountered & reported condition.
Localised scleroderma is a rare autoimmune disorder characterized by fibrosis of the skin and subcutaneous tissues. Although its etiology is not fully understood, several factors including environmental triggers and genetic predisposition have been implicated.
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