A Hypersensitivity following antivenom administration: A case report
Case Report
DOI:
https://doi.org/10.53411/jpadr.2021.2.4.6Keywords:
Snakebite, anti snake venom, hypersensitivity, anti-snake venom reactionAbstract
Introduction: Allergic reactions are the most common reported adverse events, after administration of antivenom. Antivenom is the treatment of snakebite. In many parts of the world where snakebite is prevalent, adverse reactions to snake antivenom are common. Acute reactions are mostly mild. Within an hour of exposure to antivenom, severe anaphylaxis may develop.
Case Presentation: Here, we illustrate a case of an 18-year-old female patient who had snakebite but after receiving antivenom, it was followed by local site swelling, rashes, and itching all over the body. It advanced to cellulitis and the patient recovered after a few days and was discharged after treatment. The prevention of reactions will depend mainly on improving the quality of antivenom.
References
Clark, R. F., McKinney, P. E., Chase, P. B., & Walter, F. G. (2002). Immediate and delayed allergic reactions to Crotalidae polyvalent immune Fab (ovine) antivenom. Annals of emergency medicine, 39(6), 671–676.
de Silva, H. A., Ryan, N. M., & de Silva, H. J. (2016). Adverse reactions to snake antivenom, and their prevention and treatment. British journal of clinical pharmacology, 81(3), 446–452.
Holstege, C. P., Wu, J., & Baer, A. B. (2002). Immediate hypersensitivity reaction associated with the rapid infusion of Crotalidae polyvalent immune Fab (ovine). Annals of emergency medicine, 39(6), 677–679.
Sharma, S. K., Alirol, E., Ghimire, A., Shrestha, S., Jha, R., Parajuli, S. B., Shrestha, D., Shrestha, S. J., Bista, A., Warrell, D., Kuch, U., Chappuis, F., & Taylor, W. (2019). Acute Severe Anaphylaxis in Nepali Patients with Neurotoxic Snakebite Envenoming Treated with the VINS Polyvalent Antivenom. Journal of tropical medicine, 2019, 2689171.
Zeng, F. J., Chen, C., & Liu, M. H. (2017). Allergic reactions to antivenom in a patient bitten twice by the same snake within a month: A rare case report and literature review. Chinese journal of traumatology Zhonghua chuang shang za zhi, 20(5), 299–302.
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Copyright (c) 2021 Dr. Richa Patel, Dr. Harsha Makwana, Dr. Shikha Sood, Dr. Supriya Malhotra
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